A1 Refereed original research article in a scientific journal

Evaluation of Ga-68-labeled tracers for PET imaging of myocardial perfusion in pigs



Authors: Tarkia M, Saraste A, Saanijoki T, Oikonen V, Vahasilta T, Strandberg M, Stark C, Tolvanen T, Teras M, Savunen T, Green MA, Knuuti J, Roivainen A

Publisher: ELSEVIER SCIENCE INC

Publication year: 2012

Journal: Nuclear Medicine and Biology

Journal name in source: NUCLEAR MEDICINE AND BIOLOGY

Journal acronym: NUCL MED BIOL

Number in series: 5

Volume: 39

Issue: 5

First page : 715

Last page: 723

Number of pages: 9

ISSN: 0969-8051

DOI: https://doi.org/10.1016/j.nucmedbio.2011.11.007(external)


Abstract
Conclusion: Our results revealed that myocardial accumulation of the Ga-68 chelates proposed for myocardial perfusion imaging with PET was slow and not determined by myocardial perfusion in a large animal model. These findings suggest that the studied tracers are not suitable for clinical imaging of myocardial perfusion. (C) 2012 Elsevier Inc. All rights reserved.



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