A1 Journal article – refereed

An oral challenge test with carmine red (E120) in skin prick test positive patients




List of Authors: Liippo J, Lammintausta K

Publication year: 2015

Journal: European Annals of Allergy and Clinical Immunology

Volume number: 47

Issue number: 6

Number of pages: 5

ISSN: 1764-1489


Abstract


BACKGROUND:

Positive skin prick test reactions to carmine red (E120) occur in approximately 3% of the patients studied for food allergy. Carmine ingestion associated systemic symptoms are occasionally suspected, but sufficient information of proven carmine allergy is not available.



PATIENTS AND METHODS:

To analyse carmine related symptoms in skin prick test positive patients a cohort of 23 patients with suspected allergy to carmine red was subjected to a single-blind placebo-controlled oral challenge test with carmine red.



RESULTS:

Five patients developed clinical symptoms during the placebo-controlled oral challenge. As a result, the overall frequency of clinical carmine allergy is estimated to be 0.7% in general dermatology patients studied for food-associated symptoms.



CONCLUSIONS:

Oral challenge test provides a valuable in vivo tool to better inform patients with positive skin prick tests to additives to avoid false allergy diets.





Last updated on 2021-24-06 at 10:46