Genotype Prediction of Adult Type 2 Diabetes From Adolescence in a Multiracial Population

: Vassy JL, DasMahapatra P, Meigs JB, Schork NJ, Magnussen CG, Chen W, Raitakari OT, Pencina MJ, Jamal SM, Berenson GS, Goodman E

Publisher: AMER ACAD PEDIATRICS

: 2012

: Pediatrics

: PEDIATRICS

: 5

: 130

: 5

: E1235

: E1242

: 8

: 0031-4005

DOI: https://doi.org/10.1542/peds.2012-1132(external)

CONCLUSIONS: Although a genotype score assessed among white and black adolescents is significantly associated with T2D in adulthood, it does not improve prediction over clinical risk factors. Genetic screening for T2D in its current state is not a useful addition to adolescents' clinical care. Pediatrics 2012;130:e1235-e1242