Dynamic logistic regression model and population attributable fraction to investigate the association between adherence, missed visits and mortality – a study of HIV-infected adults surviving the first year of ART

: a study of HIV-infected adults surviving the first year of ART

: Syvia Kiwuwa-Muyingo, Hannu Oja, Ann Sarah Walker, Pauliina Ilmonen, Jonathan Levin, Ivan Mambule, Andrew Reid, Peter Mugyenyi, Jim Todd, Dart Trial Team D

Publisher: BIOMED CENTRAL LTD

: 2013

: BMC Infectious Diseases

: BMC INFECTIOUS DISEASES

: BMC INFECT DIS

: ARTN 395

: 1

: 13

: 1

: 395

: 14

: 1471-2334

DOI: https://doi.org/10.1186/1471-2334-13-395

Conclusions: Recurrent poor adherence determined even through simple measures is associated with high mortality both at individual level as well as at the ART programme level. The number of lives saved through effective interventions to improve adherence could be considerable particularly for individuals monitored without using CD4 cell counts. The findings have important implications for clinical practice and for developing interventions to enhance adherence.