SYNTHESIS OF 3'-FUNCTIONALIZED OLIGONUCLEOTIDES ON A SINGLE SOLID SUPPORT




HOVINEN J, GUZAEV A, AZHAYEV A, LONNBERG H

PublisherPERGAMON-ELSEVIER SCIENCE LTD

1993

Tetrahedron Letters

TETRAHEDRON LETTERS

TETRAHEDRON LETT

34

50

8169

8172

4

0040-4039

DOIhttps://doi.org/10.1016/S0040-4039(00)61482-X



Oligodeoxyribonucleotides tethered with an amino-, carboxy-, amidocarbonyl-, or mercaptoalkyl spacer arm at 3'-terminus were obtained by assembling the chains on a modified aminoalkyl-CPG (1) and releasing them with appropriate reagents.



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