SYNTHESIS OF 3'-FUNCTIONALIZED OLIGONUCLEOTIDES ON A SINGLE SOLID SUPPORT
: HOVINEN J, GUZAEV A, AZHAYEV A, LONNBERG H
Publisher: PERGAMON-ELSEVIER SCIENCE LTD
: 1993
: Tetrahedron Letters
: TETRAHEDRON LETTERS
: TETRAHEDRON LETT
: 34
: 50
: 8169
: 8172
: 4
: 0040-4039
DOI: https://doi.org/10.1016/S0040-4039(00)61482-X
Oligodeoxyribonucleotides tethered with an amino-, carboxy-, amidocarbonyl-, or mercaptoalkyl spacer arm at 3'-terminus were obtained by assembling the chains on a modified aminoalkyl-CPG (1) and releasing them with appropriate reagents.