A1 Refereed original research article in a scientific journal

SYNTHESIS OF 3'-FUNCTIONALIZED OLIGONUCLEOTIDES ON A SINGLE SOLID SUPPORT



Authors: HOVINEN J, GUZAEV A, AZHAYEV A, LONNBERG H

Publisher: PERGAMON-ELSEVIER SCIENCE LTD

Publication year: 1993

Journal:: Tetrahedron Letters

Journal name in source: TETRAHEDRON LETTERS

Journal acronym: TETRAHEDRON LETT

Volume: 34

Issue: 50

First page : 8169

Last page: 8172

Number of pages: 4

ISSN: 0040-4039

DOI: https://doi.org/10.1016/S0040-4039(00)61482-X


Abstract
Oligodeoxyribonucleotides tethered with an amino-, carboxy-, amidocarbonyl-, or mercaptoalkyl spacer arm at 3'-terminus were obtained by assembling the chains on a modified aminoalkyl-CPG (1) and releasing them with appropriate reagents.


Research Areas



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