A1 Refereed original research article in a scientific journal
Anatomic Versus Physiologic Assessment of Coronary Artery Disease: Role of coronary flow reserve, fractional flow reserve, and positron emission tomography imaging in revascularization decision-making
Authors: Gould KL, Johnson NP, Bateman TM, Beanlands RS, Bengel FM, Bober R, Camici PG, Cerqueira MD, Chow BJW, Di Carli MF, Dorbala S, Gewirtz H, Gropler RJ, Kaufmann PA, Knaapen P, Knuuti J, Merhige ME, Rentrop KP, Ruddy TD, Schelbert HR, Schindler TH, Schwaiger M, Sdringola S, Vitarello J, Williams KA, Gordon D, Dilsizian V, Narula J
Publisher: ELSEVIER SCIENCE INC
Publication year: 2013
Journal: Journal of the American College of Cardiology
Journal name in source: JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
Journal acronym: J AM COLL CARDIOL
Number in series: 18
Volume: 62
Issue: 18
First page : 1639
Last page: 1653
Number of pages: 15
ISSN: 0735-1097
DOI: https://doi.org/10.1016/j.jacc.2013.07.076
Angiographic severity of coronary artery stenosis has historically been the primary guide to revascularization or medical management of coronary artery disease. However, physiologic severity defined by coronary pressure and/ or flow has resurged into clinical prominence as a potential, fundamental change from anatomically to physiologically guided management. This review addresses clinical coronary physiology-pressure and flowd-as clinical tools for treating patients. We clarify the basic concepts that hold true for whatever technology measures coronary physiology directly and reliably, here focusing on positron emission tomography and its interplay with intracoronary measurements.
