Haemoconcentration via diuresis in short-term hypoxia: A possible role for cardiac natriuretic peptide in rainbow trout - UTU Tutkimustietojärjestelmä

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Haemoconcentration via diuresis in short-term hypoxia: A possible role for cardiac natriuretic peptide in rainbow trout

Tekijät: Tervonen V, Vuolteenaho O, Nikinmaa M

Kustantaja: ELSEVIER SCIENCE INC

Julkaisuvuosi: 2006

Journal: Comparative Biochemistry and Physiology - Part A: Molecular and Integrative Physiology

Tietokannassa oleva lehden nimi: COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY

Lehden akronyymi: COMP BIOCHEM PHYS A

Vuosikerta: 144

Numero: 1

Aloitussivu: 86

Lopetussivu: 92

Sivujen määrä: 7

ISSN: 1095-6433

DOI: https://doi.org/10.1016/j.cbpa.2006.02.014

Tiivistelmä

Rainbow trout, exposed to acute hypoxia (decrease of oxygen level from full to 30% air saturation for I It, stable 30% air saturation for 2 h), showed more than twofold increase in urine flow rate. Hypoxic diuresis was associated with a sustained increase in dorsal aortic cardiac peptide (sCP) level, and the diuresis could be completely inhibited by a bolus injection of sCP antiserum. These results suggest that hypoxic haemoconcentration, which is partially achieved via increased urine flow rate in vertebrates, is caused by cardiac peptides. The results further suggest that cardiac peptide receptors in hypoxic fish gills modulate the postbranchial systemic level of sCP. (c) 2006 Elsevier Inc. All rights reserved.