Biodiversity loss threatens the health and viability of all kinds of ecosystems and civilization, including ours, in their present form. While business activity is a key driver of biodiversity loss, to date the lack of appreciation of the connections between biodiversity and business has been lamented. In this paper we take stock of how the business and sustainability literatures, broadly defined, has addressed biodiversity. We conducted a systematic literature review for academic articles connecting biodiversity & business appearing in 74 academic journals between 1970-2022. From a total sample of 252 articles, 42 articles were selected for inclusion in the final sample. We present our findings along four themes and ten observations that recurred in our inductive analysis. Given the fragmented state of the art in current research on biodiversity and business, in guise of synthesis, we develop an integrative analytical canvas. In closing, we offer an agenda guiding future research. The main contribution of our paper is in offering academic and business readers an overview of the present state of the art of research on biodiversity in leading academic business and sustainability journals. It is our sincere hope that by summarizing the scholarly discussion thus far we can offer the next researchers a spring board from which to jump start their subsequent explorations into this critical nexus, while inspiring business practitioners toward biodiversity protection.