High specific activity Cu-61 via Zn-64(p,alpha)Cu-61 reaction at low proton energies



: Thieme S, Walther M, Preusche S, Rajander J, Pietzsch HJ, Lill JO, Kaden M, Solin O, Steinbach J

Publisher: PERGAMON-ELSEVIER SCIENCE LTD

: 2013

: Applied Radiation and Isotopes

: APPLIED RADIATION AND ISOTOPES

: APPL RADIAT ISOTOPES

: 72

: 169

: 176

: 8

: 0969-8043

DOI: https://doi.org/10.1016/j.apradiso.2012.11.007


The PET radionuclide Cu-61 is accessible through several nuclear reactions. Besides the common production route via Ni-61(p,n)Cu-61 the Zn-64(p,alpha)Cu-61 reaction offers some advantages. Especially the comparatively cheap enriched Zn-64 makes this process economical. For fast product purification and recycling of target material an ion exchange cascade was developed. In addition a separation technique with a copper selective resin was tested. Cu-61 with specific activities up to 1000 GBq/mu mol was produced with these methods. (c) 2012 Elsevier Ltd. All rights reserved.



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