A1 Refereed original research article in a scientific journal
SUBSTRATE TRANSPORT AND UTILIZATION IN FISH ERYTHROCYTES
Authors: NIKINMAA M, TIIHONEN K
Publisher: BLACKWELL SCIENCE LTD
Publication year: 1994
Journal: Acta Physiologica Scandinavica
Journal name in source: ACTA PHYSIOLOGICA SCANDINAVICA
Journal acronym: ACTA PHYSIOL SCAND
Volume: 152
Issue: 2
First page : 183
Last page: 189
Number of pages: 7
ISSN: 0001-6772
DOI: https://doi.org/10.1111/j.1748-1716.1994.tb09798.x
Abstract
In contrast to mammalian erythrocytes which fulfil their energy requirements via anaerobic glycolysis, fish erythrocytes obtain most of their energy aerobically via the Krebs cycle. This enables them to use various substrates, including monocarboxylic acids, glucose and amino acids. This review discusses the membrane permeability of these substrates, and their relative importance in the energy production of fish erythrocytes. Agnathans are characterized by a high permeability to all of the potential substrates, glucose, monocarboxylic and amino acids. In contrast, teleost erythrocytes are often characterized by low glucose permeability. It appears that monocarboxylic acids and certain amino acids such as glutamine may be more important in energy production of teleost erythrocytes than glucose.
In contrast to mammalian erythrocytes which fulfil their energy requirements via anaerobic glycolysis, fish erythrocytes obtain most of their energy aerobically via the Krebs cycle. This enables them to use various substrates, including monocarboxylic acids, glucose and amino acids. This review discusses the membrane permeability of these substrates, and their relative importance in the energy production of fish erythrocytes. Agnathans are characterized by a high permeability to all of the potential substrates, glucose, monocarboxylic and amino acids. In contrast, teleost erythrocytes are often characterized by low glucose permeability. It appears that monocarboxylic acids and certain amino acids such as glutamine may be more important in energy production of teleost erythrocytes than glucose.
UTU Research Portal