A1 Refereed original research article in a scientific journal

Oral treatment with a vitamin D3 analogue (BXL628) has anti-inflammatory effects in rodent model of interstitial cystitis



Authors: Benigni F, Baroni E, Zecevic M, Zvara P, Streng T, Hedlund P, Colli E, D'Ambrosio D, Andersson KE

Publisher: BLACKWELL PUBLISHING

Publication year: 2006

Journal:BJU International

Journal name in sourceBJU INTERNATIONAL

Journal acronym: BJU INT

Volume: 97

Issue: 3

First page : 617

Last page: 624

Number of pages: 8

ISSN: 1464-4096

DOI: https://doi.org/10.1111/j.1464-410X.2006.05971.x


Abstract
Vitamin D3 analogues may successfully be used as anti-inflammatory agents in allergen-mediated inflammatory reactions. Moreover, the modulatory effect shown on mast cell activation by the BXL628 analogue strongly supports its potential therapeutic use in a possibly mast cell-dependent disease such as human interstitial cystitis.



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