A1 Refereed original research article in a scientific journal

Prostatic inflammation and obstructive voiding in the adult Noble rat: Impact of the testosterone to estradiol ratio in serum




AuthorsBernoulli J, Yatkin E, Konkol Y, Talvitie EM, Santti R, Streng T

PublisherWILEY-LISS

Publication year2008

Journal:Prostate

Journal name in sourcePROSTATE

Journal acronymPROSTATE

Volume68

Issue12

First page 1296

Last page1306

Number of pages11

ISSN0270-4137

DOIhttps://doi.org/10.1002/pros.20791


Abstract
CONCLUSIONS. Different responses of the prostatic inflammation and voiding function to the change in T-to-E-2 ratio imply that non-bacterial prostatic inflammation is not a sufficient condition for the development of obstructive voiding. The present study finds no support for the idea that age- and/or obesity-related hypoandrogenic state with a decreased ratio of T-to-E-2 would cause urethral obstruction.



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