A1 Refereed original research article in a scientific journal
Prostatic inflammation and obstructive voiding in the adult Noble rat: Impact of the testosterone to estradiol ratio in serum
Authors: Bernoulli J, Yatkin E, Konkol Y, Talvitie EM, Santti R, Streng T
Publisher: WILEY-LISS
Publication year: 2008
Journal:Prostate
Journal name in sourcePROSTATE
Journal acronym: PROSTATE
Volume: 68
Issue: 12
First page : 1296
Last page: 1306
Number of pages: 11
ISSN: 0270-4137
DOI: https://doi.org/10.1002/pros.20791
Abstract
CONCLUSIONS. Different responses of the prostatic inflammation and voiding function to the change in T-to-E-2 ratio imply that non-bacterial prostatic inflammation is not a sufficient condition for the development of obstructive voiding. The present study finds no support for the idea that age- and/or obesity-related hypoandrogenic state with a decreased ratio of T-to-E-2 would cause urethral obstruction.
CONCLUSIONS. Different responses of the prostatic inflammation and voiding function to the change in T-to-E-2 ratio imply that non-bacterial prostatic inflammation is not a sufficient condition for the development of obstructive voiding. The present study finds no support for the idea that age- and/or obesity-related hypoandrogenic state with a decreased ratio of T-to-E-2 would cause urethral obstruction.