A1 Refereed original research article in a scientific journal

Transient Receptor Potential A1 (TRPA1) Activity in the Human Urethra-Evidence for a Functional Role for TRPA1 in the Outflow Region




AuthorsGratzke C, Streng T, Waldkirch E, Sigl K, Stief C, Andersson KE, Hedlund P

PublisherELSEVIER SCIENCE BV

Publication year2009

Journal:European Urology

Journal name in sourceEUROPEAN UROLOGY

Journal acronymEUR UROL

Volume55

Issue3

First page 696

Last page704

Number of pages9

ISSN0302-2838

DOIhttps://doi.org/10.1016/j.eururo.2008.04.042


Abstract
Conclusions: The localization of TRPA1 to nerves that also express TRPV1 and CGRP, and in urothelial cells and interstitial cells, as well as the findings that TRPA1 agonists can modify tone of urethral preparations, propose a role for TRPA1 in afferent and efferent sensory signaling of the human outflow region. (C) 2008 European Association of Urology. Published by Elsevier B.V. All rights reserved



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