A1 Refereed original research article in a scientific journal
Transient Receptor Potential A1 (TRPA1) Activity in the Human Urethra-Evidence for a Functional Role for TRPA1 in the Outflow Region
Authors: Gratzke C, Streng T, Waldkirch E, Sigl K, Stief C, Andersson KE, Hedlund P
Publisher: ELSEVIER SCIENCE BV
Publication year: 2009
Journal:: European Urology
Journal name in source: EUROPEAN UROLOGY
Journal acronym: EUR UROL
Volume: 55
Issue: 3
First page : 696
Last page: 704
Number of pages: 9
ISSN: 0302-2838
DOI: https://doi.org/10.1016/j.eururo.2008.04.042
Abstract
Conclusions: The localization of TRPA1 to nerves that also express TRPV1 and CGRP, and in urothelial cells and interstitial cells, as well as the findings that TRPA1 agonists can modify tone of urethral preparations, propose a role for TRPA1 in afferent and efferent sensory signaling of the human outflow region. (C) 2008 European Association of Urology. Published by Elsevier B.V. All rights reserved
Conclusions: The localization of TRPA1 to nerves that also express TRPV1 and CGRP, and in urothelial cells and interstitial cells, as well as the findings that TRPA1 agonists can modify tone of urethral preparations, propose a role for TRPA1 in afferent and efferent sensory signaling of the human outflow region. (C) 2008 European Association of Urology. Published by Elsevier B.V. All rights reserved