Elevated Maternal C-Reactive Protein and Increased Risk of Schizophrenia in a National Birth Cohort - UTU Research Portal

A1 Refereed original research article in a scientific journal

Elevated Maternal C-Reactive Protein and Increased Risk of Schizophrenia in a National Birth Cohort

Authors: Sarah Canetta, Andre Sourander, Heljä-Marja Surcel, Susanna Hinkka-Yli-Salomäki, Jaana Leiviskä, Christoph Kellendonk, Ian W. McKeague, Alan S. Brown

Publisher: AMER PSYCHIATRIC PUBLISHING, INC

Publication year: 2014

Journal: American Journal of Psychiatry

Journal name in source: AMERICAN JOURNAL OF PSYCHIATRY

Journal acronym: AM J PSYCHIAT

Volume: 171

Issue: 9

First page : 960

Last page: 968

Number of pages: 9

ISSN: 0002-953X

eISSN: 1535-7228

DOI: https://doi.org/10.1176/appi.ajp.2014.13121579

Abstract

Conclusions: This finding provides the most robust evidence to date that maternal inflammation may play a significant role in schizophrenia, with possible implications for identifying preventive strategies and pathogenic mechanisms in schizophrenia and other neurodevelopmental disorders.