Vertaisarvioitu katsausartikkeli tieteellisessä aikakauslehdessä (A2)

Early diabetic eye damage: Comparing detection methods using diagnostic power




Julkaisun tekijätRai Bhim B, van Kleef Joshua P, Sabeti Faran, Vlieger Robin, Suominen Hanna, Maddess Ted

KustantajaElsevier Inc

Julkaisuvuosi2023

JournalSurvey of Ophthalmology

Tietokannassa oleva lehden nimiSurvey of ophthalmology

Lehden akronyymiSurv Ophthalmol

Volyymi69

Julkaisunumero1

Aloitussivu24

Lopetussivun numero33

ISSN0039-6257

eISSN1879-3304

DOIhttp://dx.doi.org/10.1016/j.survophthal.2023.09.002

Verkko-osoitehttps://doi.org/10.1016/j.survophthal.2023.09.002

Rinnakkaistallenteen osoitehttps://research.utu.fi/converis/portal/detail/Publication/181761532


Tiivistelmä
It is now clear that retinal neuropathy precedes classical microvascular retinopathy in diabetes. Therefore, tests that underpin useful new endpoints must provide high diagnostic power well before the onset of moderate diabetic retinopathy. Hence, we compare detection methods of early diabetic eye damage. We reviewed data from a range of functional and structural studies of early diabetic eye disease and computed standardized effect size as a measure of diagnostic power, allowing the studies to be compared quantitatively. We then derived minimum performance criteria for tests to provide useful clinical endpoints. This included the criteria that tests should be rapid and easy so that children with type 1 diabetes can be followed into adulthood with the same tests. We also defined attributes that lend test data to further improve performance using Machine/Deep Learning. Data from a new form of objective perimetry suggested that the criteria are achievable.

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Last updated on 2023-28-11 at 13:28