Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1)
Incidence and outcome of perforations during medium vessel occlusion compared with large vessel occlusion thrombectomy
Julkaisun tekijät: Schulze-Zachau Victor, Brehm Alex, Ntoulias Nikolaos, Krug Nadja, Tsogkas Ioannis, Blackham Kristine Ann, Möhlenbruch Markus A, Jesser Jessica, Cervo Amedeo, Kreiser Kornelia, Althaus Katharina, Maslias Errikos, Michel Patrik, Saliou Guillaume, Riegler Christoph, Nolte Christian H, Maier Ilko, Jamous Ala, Rautio Riitta, Ylikotila Pauli, Fargen Kyle M, Wolfe Stacey Q, Castellano Davide, Boghi Andrea, Kaiser Daniel P O, Cuberi Ani, Kirschke Jan S, Schwarting Julian, Limbucci Nicola, Renieri Leonardo, Al Kasab Sami, Spiotta Alejandro M, Fragata Isabel, Rodriquez-Ares Tania, Maurer Christoph Johannes, Berlis Ansgar, Moreu Manuel, López-Frías Alfonso, Pérez-García Carlos, Commodaro Christian, Pileggi Marco, Mascitelli Justin, Giordano Flavio, Casagrande Walter, Purves Cynthia P, Bester Maxim, Flottmann Fabian, Kan Peter T, Edhayan Gautam, Hofmeister Jeremy, Machi Paolo, Kaschner Marius, Weiss Daniel, Katan Mira, Fischer Urs, Psychogios Marios-Nikos
Kustantaja: BMJ PUBLISHING GROUP
Julkaisuvuosi: 2023
Journal: Journal of NeuroInterventional Surgery
Tietokannassa oleva lehden nimi: JOURNAL OF NEUROINTERVENTIONAL SURGERY
Lehden akronyymi: J NEUROINTERV SURG
Sivujen määrä: 7
ISSN: 1759-8478
eISSN: 1759-8486
DOI: http://dx.doi.org/10.1136/jnis-2023-020531
Verkko-osoite: https://jnis.bmj.com/content/early/2023/07/31/jnis-2023-020531
Background
Vessel perforation during thrombectomy is a severe complication and is hypothesized to be more frequent during medium vessel occlusion (MeVO) thrombectomy. The aim of this study was to compare the incidence and outcome of patients with perforation during MeVO and large vessel occlusion (LVO) thrombectomy and to report on the procedural steps that led to perforation.
Methods
In this multicenter retrospective cohort study, data of consecutive patients with vessel perforation during thrombectomy between January 1, 2015 and September 30, 2022 were collected. The primary outcomes were independent functional outcome (ie, modified Rankin Scale 0-2) and all-cause mortality at 90 days. Binomial test, chi-squared test and t-test for unpaired samples were used for statistical analysis.
Results
During 25 769 thrombectomies (5124 MeVO, 20 645 LVO) in 25 stroke centers, perforation occurred in 335 patients (1.3%; mean age 72 years, 62% female). Perforation occurred more often in MeVO thrombectomy (2.4%) than in LVO thrombectomy (1.0%, p<0.001). More MeVO than LVO patients with perforation achieved functional independence at 3 months (25.7% vs 10.9%, p=0.001). All-cause mortality did not differ between groups (overall 51.6%). Navigation beyond the occlusion and retraction of stent retriever/aspiration catheter were the two most common procedural steps that led to perforation.
Conclusions
In our cohort, perforation was approximately twice as frequent in MeVO than in LVO thrombectomy. Efforts to optimize the procedure may focus on navigation beyond the occlusion site and retraction of stent retriever/aspiration catheter. Further research is necessary in order to identify thrombectomy candidates at high risk of intraprocedural perforation and to provide data on the effectiveness of endovascular countermeasures.
