Refereed journal article or data article (A1)
Computed tomographic angiography in coronary artery disease
List of Authors: Serruys Patrick W, Kotoku Nozomi, Nørgaard Bjarne L, Garg Scot, Nieman Koen, Dweck Marc R, Bax Jeroen J, Knuuti Juhani, Narula Jagat, Perera Divaka, Taylor Charles A, Leipsic Jonathon A, Nicol Edward D, Piazza Nicolo, Schultz Carl J, Kitagawa Kakuya, Bruyne Bernard, Collet Carlos, Tanaka Kaoru, Mushtaq Saima, Belmonte Marta, Dudek Darius, Zlahoda-Huzior Adriana, Tu Shengxian, Wijns William, Sharif Faisal, Budoff Matthew J, Mey Johan, Andreini Daniele, Onuma Yoshinobu
Publisher: Europa Digital & Publishing
Publication year: 2023
Journal: Eurointervention
Journal name in source: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology
Journal acronym: EuroIntervention
Volume number: 18
Issue number: 16
Start page: e1307
End page: e1327
ISSN: 1774-024X
eISSN: 1969-6213
DOI: http://dx.doi.org/10.4244/EIJ-D-22-00776
URL: https://doi.org/10.4244/EIJ-D-22-00776
Coronary computed tomographic angiography (CCTA) is becoming the first-line investigation for establishing the presence of coronary artery disease and, with fractional flow reserve (FFRCT), its haemodynamic significance. In patients without significant epicardial obstruction, its role is either to rule out atherosclerosis or to detect subclinical plaque that should be monitored for plaque progression/regression following prevention therapy and provide risk classification. Ischaemic non-obstructive coronary arteries are also expected to be assessed by non-invasive imaging, including CCTA. In patients with significant epicardial obstruction, CCTA can assist in planning revascularisation by determining the disease complexity, vessel size, lesion length and tissue composition of the atherosclerotic plaque, as well as the best fluoroscopic viewing angle; it may also help in selecting adjunctive percutaneous devices (e.g., rotational atherectomy) and in determining the best landing zone for stents or bypass grafts.
