Comparative assessment of segmentation algorithms for tumor delineation on a test-retest [C-11]choline dataset

: Tomasi G, Shepherd T, Turkheimer F, Visvikis D, Aboagye E

Publisher: AMER ASSOC PHYSICISTS MEDICINE AMER INST PHYSICS

: 2012

Medical Physics

: MEDICAL PHYSICS

: MED PHYS

: 12

: 39

: 12

: 7571

: 7579

: 9

: 0094-2405

DOI: https://doi.org/10.1118/1.4761952

Conclusions: The TV variability obtained with the best methods was similar to the one reported for TV in previous [F-18] FDG and [F-18] FLT studies and to the one of SUVMAX/SUVMEAN on the authors' [C-11] choline dataset. The good reproducibility of [C-11] choline TV warrants further studies to test whether TV could predict early response to treatment and survival, as for [F-18] FDG, to complement/substitute the use of SUVMAX and SUVMEAN. (C) 2012 American Association of Physicists in Medicine. [http://dx.doi.org/10.1118/1.4761952]