This introductory chapter briefly outlines the main theme of this volume, namely, to review the new opportunities and risks of digital healthcare from various disciplinary perspectives. These perspectives include law, public policy, organisational studies, and applied ethics. Based on this interdisciplinary approach, we hope that effective strategies may arise to ensure that benefits of this ongoing revolution are deployed in a responsible and sustainable manner. The second part of the chapter comprises a brief review of the four parts and fourteen substantive chapters that make up this volume.