B1 Non-refereed article in a scientific journal
Does reactivation of cytomegalovirus contribute to severe COVID-19 disease?
Authors: Soderberg-Naucler Cecilia
Publisher: BMC
Publication year: 2021
Journal: Immunity and Ageing
Journal name in source: IMMUNITY & AGEING
Journal acronym: IMMUN AGEING
Article number: 12
Volume: 18
Number of pages: 7
DOI: https://doi.org/10.1186/s12979-021-00218-z(external)
Abstract
The majority of people infected with SARS-CoV-2 are asymptomatic or have mild to moderate symptoms. However, for unknown reasons, about 15 % have severe pneumonia requiring hospital care and oxygen support, and about 5 % develop acute respiratory distress syndrome, septic shock, and multiorgan failure that result in a high mortality rate. The risk of severe COVID-19 is highest among those who are over 70 years of age. Why severe COVID-19 develops in some people but not others is not understood. Could some cases involve reactivation of latent cytomegalovirus (CMV)?
The majority of people infected with SARS-CoV-2 are asymptomatic or have mild to moderate symptoms. However, for unknown reasons, about 15 % have severe pneumonia requiring hospital care and oxygen support, and about 5 % develop acute respiratory distress syndrome, septic shock, and multiorgan failure that result in a high mortality rate. The risk of severe COVID-19 is highest among those who are over 70 years of age. Why severe COVID-19 develops in some people but not others is not understood. Could some cases involve reactivation of latent cytomegalovirus (CMV)?
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