Purpose: To evaluate the success of monolithic endocrowns fabricated using a digital workflow.

Materials and Methods: Twenty-three patients requiring restoration of devitalized molars or premolars were included in the study. The preparation was scanned using an intraoral scanner (Cerec Bluecam, Dentsply Sirona), and a monolithic restoration was made from a nanoparticle resin-based hybrid composite (#10 Cerasmart [CS]; #10 Lava Ultimate [LU], 3M Espe) or a polymer-infiltrated ceramic (#10 Vita Enamic [VE]). At the time of placement and after 6 months, 1 year, and 5 years of function, radiographs were taken to evaluate the marginal integrity of the restorations, and clinical pictures were taken to assess the quality of the restoration using the USPHS criteria.

Results: After 5 years, the restorative success rate was 70.8%, the restorative survival rate was 87.5%, and the tooth survival was 91.6%. Four chippings (two LU, two CS), three fractures (three LU), and two debonding of the restorations (two CS) occurred. Also, two teeth were extracted after 5 years of follow-up (two VE) because of secondary caries and a root fracture. The USPHS ratings were high, except for color match, which was rated the lowest at all time intervals.

Conclusion: Nanoceramic endocrowns made using a completely digital workflow have an acceptable survival rate after 5 years. However, the complication rate was high.