A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä

Staging right heart failure in patients with tricuspid regurgitation undergoing tricuspid surgery




TekijätGalloo Xavier, Stassen Jan, Butcher Steele C., Meucci Maria Chiara, Dietz Marlieke F., Mertens Bart J.A., Prihadi Edgard A., van der Bijl Pieter, Marsan Nina Ajmone, Braun Jerry, Bax Jeroen J., Delgado Victoria

KustantajaOXFORD UNIV PRESS INC

Julkaisuvuosi2022

JournalEuropean Journal of Cardio-Thoracic Surgery

Lehden akronyymiEUR J CARDIO-THORAC

Vuosikerta62

Numero2

Sivujen määrä9

ISSN1010-7940

eISSN1873-734X

DOIhttps://doi.org/10.1093/ejcts/ezac290


Tiivistelmä

OBJECTIVES: This study evaluated the prognostic value of staging right heart failure in patients with significant tricuspid regurgitation (TR) undergoing tricuspid valve (TV) surgery.

METHODS: Patients with significant TR who underwent TV surgery were divided into 4 right heart failure stages according to the presence of right ventricular (RV) dysfunction and clinical signs of right heart failure: stage 1 was defined as no RV dysfunction and no signs of right heart failure; stage 2 indicated RV dysfunction without signs of right heart failure; stage 3 included RV dysfunction and signs of right heart failure; and stage 4 was defined as RV dysfunction and refractory signs of right heart failure at rest.

RESULTS: A total of 278 patients [mean age 64 (12), 49% males] were included, of whom 34 (12%) patients were classified as stages 1 and 2, 141 (51%) as stage 3 and 103 (37%) as stage 4 right heart failure. The majority of patients (91%) had TV surgery concomitant to left-sided valve surgery or coronary artery bypass grafting and 95% underwent TV annuloplasty. Cumulative survival rates were 89%, 78% and 61% at 1 month, 1 year and 5 years, respectively. Stages 1 and 2 and stage 3 were independently associated with better survival compared to stage 4 (hazard ratio: 0.391 [95% confidence interval: 0.186-0.823] and 0.548 [95% confidence interval: 0.369-0.813], respectively).

CONCLUSIONS: Patients with significant TR undergoing TV surgery and diagnosed without advanced right heart failure have better survival as compared to patients with right heart failure.



Last updated on 2024-26-11 at 15:08