Vertaisarvioitu katsausartikkeli tieteellisessä aikakauslehdessä (A2)
Applications of PET in diabetes research
Julkaisun tekijät: Nuutila P
Julkaisuvuosi: 1997
Journal: Hormone and Metabolic Research
Tietokannassa oleva lehden nimi: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme
Lehden akronyymi: Horm Metab Res
Volyymi: 29
Julkaisunumero: 7
Aloitussivu: 337
Lopetussivun numero: 9
ISSN: 0018-5043
DOI: http://dx.doi.org/10.1055/s-2007-979048
Tiivistelmä
Use of positron emission tomography (PET) combined with 18F-fluoro-2-deoxy-D-glucose (18FDG) allows a noninvasive quantitation of glucose uptake in individual tissues such as human muscles and heart. Using 15O-labelled water and 18FDG the role of blood flow as a regulator of glucose metabolism can be studied with PET. PET has allowed study of the factors regulating heart glucose uptake in normal subjects and in subjects with alterations in skeletal muscle insulin sensitivity, and has provided evidence that insulin stimulated rates of blood flow and glucose uptake do not co-localize within muscle tissues.
Use of positron emission tomography (PET) combined with 18F-fluoro-2-deoxy-D-glucose (18FDG) allows a noninvasive quantitation of glucose uptake in individual tissues such as human muscles and heart. Using 15O-labelled water and 18FDG the role of blood flow as a regulator of glucose metabolism can be studied with PET. PET has allowed study of the factors regulating heart glucose uptake in normal subjects and in subjects with alterations in skeletal muscle insulin sensitivity, and has provided evidence that insulin stimulated rates of blood flow and glucose uptake do not co-localize within muscle tissues.
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