A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä
Preconceptual leptin levels in gestational diabetes and hypertensive pregnancy
Tekijät: Peltokorpi Antti, Lisinen Irina, Viikari Liisa, Kaaja Risto
Kustantaja: TAYLOR & FRANCIS INC
Julkaisuvuosi: 2022
Journal: Hypertension in Pregnancy
Tietokannassa oleva lehden nimi: HYPERTENSION IN PREGNANCY
Lehden akronyymi: HYPERTENS PREGNANCY
Vuosikerta: 41
Numero: 1
Aloitussivu: 70
Lopetussivu: 77
Sivujen määrä: 8
ISSN: 1064-1955
DOI: https://doi.org/10.1080/10641955.2022.2033763
Rinnakkaistallenteen osoite: https://research.utu.fi/converis/portal/detail/Publication/174865307
Pregnancy - induced hypertension (PIH), preeclampsia (PE), and gestational diabetes (GDM) are common adverse outcomes in pregnancy.
Objective
To find out whether preconceptual leptin levels differ in subsequent pregnancy between control vs. GDM and hypertensive pregnancy groups.
Materials and Methods
Data was from The Cardiovascular Risk in Young Finns Study and The Medical Birth Register of Finland. Of 293 subjects 71 developed GDM, 27 PIH/PE and 201 were controls.
Results
Leptin was higher in GDM (p < 0.0001) and PIH/PE (p = 0.0002) groups compared to control. GDM group was robust to BMI matching (p = 0,0081).
Conclusion
Leptin was higher in GDM (p < 0.0001) and PIH/PE (p = 0.0002) groups compared to control. GDM group was robust to BMI matching (p = 0,0081).
Ladattava julkaisu This is an electronic reprint of the original article. |  |
