A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä
The effects of d-amphetamine on extrastriatal dopamine D-2/D-3 receptors: a randomized, double-blind, placebo-controlled PET study with [C-11]FLB 457 in healthy subjects
Tekijät: Aalto S, Hirvonen J, Kaasinen V, Hagelberg N, Kajander J, Nagren K, Seppala T, Rinne JO, Scheinin H, Hietala J
Kustantaja: SPRINGER
Julkaisuvuosi: 2009
Journal: European Journal of Nuclear Medicine and Molecular Imaging
Tietokannassa oleva lehden nimi: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
Lehden akronyymi: EUR J NUCL MED MOL I
Vuosikerta: 36
Numero: 3
Aloitussivu: 475
Lopetussivu: 483
Sivujen määrä: 9
ISSN: 1619-7070
DOI: https://doi.org/10.1007/s00259-008-0969-9
Tiivistelmä
This placebo-controlled study showed that d-amphetamine does not induce marked changes in measures of extrastriatal dopamine D-2/D-3 receptor binding. Our results indicate that [C-11]FLB 457 PET is not a useful method for measuring extrastriatal dopamine release in humans.
This placebo-controlled study showed that d-amphetamine does not induce marked changes in measures of extrastriatal dopamine D-2/D-3 receptor binding. Our results indicate that [C-11]FLB 457 PET is not a useful method for measuring extrastriatal dopamine release in humans.