Brain white matter expansion in human obesity and the recovering effect of dieting




Haltia LT, Viljanen A, Parkkola R, Kemppainen N, Rinne JO, Nuutila P, Kaasinen V

PublisherENDOCRINE SOC

2007

Journal of Clinical Endocrinology and Metabolism

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

J CLIN ENDOCR METAB

92

8

3278

3284

7

0021-972X

DOIhttps://doi.org/10.1210/jc.2006-2495



Conclusions: The precise mechanism for the discovered white matter changes remains unclear, but the present study demonstrates that obesity and dieting are associated with opposite changes in brain structure. It is not excluded that white matter expansion in obesity has a role in the neuropathogenesis of degenerative brain diseases.



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