A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä
Interaction of Campylobacter spp. and Human Probiotics in Chicken Intestinal Mucus
Tekijät: Ganan M, Martinez-Rodriguez AJ, Carrascosa AV, Vesterlund S, Salminen S, Satokari R
Kustantaja: WILEY-BLACKWELL
Julkaisuvuosi: 2013
Journal: Zoonoses and Public Health
Tietokannassa oleva lehden nimi: ZOONOSES AND PUBLIC HEALTH
Lehden akronyymi: ZOONOSES PUBLIC HLTH
Numero sarjassa: 2
Vuosikerta: 60
Numero: 2
Aloitussivu: 141
Lopetussivu: 148
Sivujen määrä: 8
ISSN: 1863-1959
DOI: https://doi.org/10.1111/j.1863-2378.2012.01510.x
Tiivistelmä
Campylobacter is the most common cause of bacterial food-borne diarrhoeal disease throughout the world. The principal risk of human contamination is handling and consumption of contaminated poultry meat. To colonize poultry, Campylobacter adheres to and persists in the mucus layer that covers the intestinal epithelium. Inhibiting adhesion to the mucus could prevent colonization of the intestine. The aim of this study was to investigate in vitro the protective effect of defined commercial human probiotic strains on the adhesion of Campylobacter spp. to chicken intestinal mucus, in a search for alternatives to antibiotics to control this food-borne pathogen. The probiotic strains Lactobacillus rhamnosus GG and Propionibacterium freudenreichii ssp. shermanii JS and a starter culture strain Lactococcus lactis ssp. lactis adhered well to chicken intestinal mucus and were able to reduce the binding of Campylobacter spp. when the mucus was colonized with the probiotic strain before contacting the pathogen. Human-intended probiotics could be useful as prophylactics in poultry feeding for controlling Campylobacter spp. colonization.
Campylobacter is the most common cause of bacterial food-borne diarrhoeal disease throughout the world. The principal risk of human contamination is handling and consumption of contaminated poultry meat. To colonize poultry, Campylobacter adheres to and persists in the mucus layer that covers the intestinal epithelium. Inhibiting adhesion to the mucus could prevent colonization of the intestine. The aim of this study was to investigate in vitro the protective effect of defined commercial human probiotic strains on the adhesion of Campylobacter spp. to chicken intestinal mucus, in a search for alternatives to antibiotics to control this food-borne pathogen. The probiotic strains Lactobacillus rhamnosus GG and Propionibacterium freudenreichii ssp. shermanii JS and a starter culture strain Lactococcus lactis ssp. lactis adhered well to chicken intestinal mucus and were able to reduce the binding of Campylobacter spp. when the mucus was colonized with the probiotic strain before contacting the pathogen. Human-intended probiotics could be useful as prophylactics in poultry feeding for controlling Campylobacter spp. colonization.
Turun yliopiston Tutkimustietojärjestelmän portaali