A1 Refereed original research article in a scientific journal
Utilization of PET imaging in differential diagnostics between a tumefactive multiple sclerosis lesion and low-grade glioma
Authors: Tarkkonen A, Rissanen E, Tuokkola T, Airas L
Publisher: ELSEVIER SCI LTD
Publication year: 2016
Journal: Multiple Sclerosis and Related Disorders
Journal name in source: MULTIPLE SCLEROSIS AND RELATED DISORDERS
Journal acronym: MULT SCLER RELAT DIS
Volume: 9
First page : 147
Last page: 149
Number of pages: 3
ISSN: 2211-0348
DOI: https://doi.org/10.1016/j.msard.2016.07.016(external)
Abstract
We present a case where a 30-year-old man with a history of combined MS and Charcot-Marie-Tooth (CMT I) disease was additionally diagnosed and treated for grade II glioma (astrocytoma). Tumefactive MS and gliomas are sometimes difficult to distinguish from one another based on conventional magnetic resonance imaging (MRI). In our case, positron emission tomography (PET) scans with C-11-methionine (C-11-MET) and C-11-PK11195 radioligands were performed to aid in differential diagnostics. The diagnosis was confirmed finally by brain biopsy. The usefulness of PET imaging in differential diagnostics between tumefactive MS and glioma is discussed. (C) 2016 Elsevier B.V. All rights reserved.
We present a case where a 30-year-old man with a history of combined MS and Charcot-Marie-Tooth (CMT I) disease was additionally diagnosed and treated for grade II glioma (astrocytoma). Tumefactive MS and gliomas are sometimes difficult to distinguish from one another based on conventional magnetic resonance imaging (MRI). In our case, positron emission tomography (PET) scans with C-11-methionine (C-11-MET) and C-11-PK11195 radioligands were performed to aid in differential diagnostics. The diagnosis was confirmed finally by brain biopsy. The usefulness of PET imaging in differential diagnostics between tumefactive MS and glioma is discussed. (C) 2016 Elsevier B.V. All rights reserved.
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