A1 Refereed original research article in a scientific journal

Comparison of pharmacokinetic profile of levodopa throughout the day between levodopa/carbidopa/entacapone and levodopa/carbidopa when administered four or five times daily



Authors: Kuoppamaki M, Korpela K, Marttila R, Kaasinen V, Hartikainen P, Lyytinen J, Kaakkola S, Hanninen J, Loyttyniemi E, Kailajarvi M, Ruokoniemi P, Ellmen J

Publisher: SPRINGER

Publication year: 2009

Journal: European Journal of Clinical Pharmacology

Journal name in source: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

Journal acronym: EUR J CLIN PHARMACOL

Volume: 65

Issue: 5

First page : 443

Last page: 455

Number of pages: 13

ISSN: 0031-6970

DOI: https://doi.org/10.1007/s00228-009-0622-y


Abstract
The present results on the differences in levodopa PK between LCE and LC provide a basis to evaluate the relationship of levodopa PK and the induction of motor complications in an on-going study in early Parkinson's disease using similar dosing regimens.



Last updated on 2024-26-11 at 17:05