A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä
The interferon-induced helicase IFIH1 Ala946Thr polymorphism is associated with type 1 diabetes in both the high-incidence Finnish and the medium-incidence Hungarian populations
Tekijät: Jermendy A, Szatmari I, Laine AP, Lukacs K, Horvath KH, Korner A, Madacsy L, Veijola R, Simell O, Knip M, Ilonen J, Hermann R
Kustantaja: SPRINGER
Julkaisuvuosi: 2010
Journal: Diabetologia
Tietokannassa oleva lehden nimi: DIABETOLOGIA
Lehden akronyymi: DIABETOLOGIA
Numero sarjassa: 1
Vuosikerta: 53
Numero: 1
Aloitussivu: 98
Lopetussivu: 102
Sivujen määrä: 5
ISSN: 0012-186X
DOI: https://doi.org/10.1007/s00125-009-1561-y
Tiivistelmä
This study represents the first independent confirmation of the association between type 1 diabetes and the IFIH1 gene in Hungarian and Finnish populations. Summarising the data published so far, a clear association between the Ala946Thr polymorphism and type 1 diabetes was detected, with an apparent difference in the contribution to disease susceptibility in different populations of European ancestry.
This study represents the first independent confirmation of the association between type 1 diabetes and the IFIH1 gene in Hungarian and Finnish populations. Summarising the data published so far, a clear association between the Ala946Thr polymorphism and type 1 diabetes was detected, with an apparent difference in the contribution to disease susceptibility in different populations of European ancestry.
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