A1 Refereed original research article in a scientific journal
Cardiomyocyte Apoptosis After Antegrade and Retrograde Cardioplegia During Aortic Valve Surgery
Authors: Vahasilta T, Malmberg M, Saraste A, Koskenvuo JW, Parkka JP, Valtonen M, Leino K, Nuutila K, Saukko P, Kuttila K, Savunen T
Publisher: ELSEVIER SCIENCE INC
Publication year: 2011
Journal: Annals of Thoracic Surgery
Journal name in source: ANNALS OF THORACIC SURGERY
Journal acronym: ANN THORAC SURG
Number in series: 4
Volume: 92
Issue: 4
First page : 1351
Last page: 1357
Number of pages: 7
ISSN: 0003-4975
DOI: https://doi.org/10.1016/j.athoracsur.2011.05.065(external)
Abstract
Conclusions. In contrast to antegrade cardioplegia, retrograde cardioplegia is associated with increased cardiomyocyte apoptosis, impaired immediate postoperative systolic function, and lack of long-term favorable left ventricle remodeling after aortic valve replacement, suggesting inadequate myocardial protection. (Ann Thorac Surg 2011;92:1351-7) (C) 2011 by The Society of Thoracic Surgeons
Conclusions. In contrast to antegrade cardioplegia, retrograde cardioplegia is associated with increased cardiomyocyte apoptosis, impaired immediate postoperative systolic function, and lack of long-term favorable left ventricle remodeling after aortic valve replacement, suggesting inadequate myocardial protection. (Ann Thorac Surg 2011;92:1351-7) (C) 2011 by The Society of Thoracic Surgeons
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