Cognitive slowing in Parkinson's disease is related to frontostriatal dopaminergic dysfunction

: Jokinen P, Karrasch M, Bruck A, Johansson J, Bergman J, Rinne JO

Publisher: ELSEVIER SCIENCE BV

: 2013

: Journal of the Neurological Sciences

: JOURNAL OF THE NEUROLOGICAL SCIENCES

: J NEUROL SCI

: 1-2

: 329

: 1-2

: 23

: 28

: 6

: 0022-510X

DOI: https://doi.org/10.1016/j.jns.2013.03.006

Conclusion: Our study indicates that dopaminergic dysfunction within neural networks linking striatum to prefrontal cortex is involved in the slowing of both automatic and controlled cognitive processing in PD patients. (C) 2013 Elsevier B.V. All rights reserved.