The same annual dose of 292000 IU of vitamin D-3 (cholecalciferol) on either daily or four monthly basis for elderly women: 1-year comparative study of the effects on serum 25(OH)D-3 concentrations and renal function
: Pekkarinen T, Valimaki VV, Aarum S, Turpeinen U, Hamalainen E, Loyttyniemi E, Valimaki MJ
Publisher: WILEY-BLACKWELL
: 2010
: Clinical Endocrinology
: CLINICAL ENDOCRINOLOGY
: CLIN ENDOCRINOL
: 4
: 72
: 4
: 455
: 461
: 7
: 0300-0664
DOI: https://doi.org/10.1111/j.1365-2265.2009.03637.x
In terms of serum 25(OH)D-3 concentrations, 800 IU daily was more efficient than a 97333 IU every 4 months. However, to increase adherence, the latter is still worth developing. Both treatments increased urinary excretion of calcium, but did not worsen renal function.