G2 Master’s thesis, polytechnic Master’s thesis

An accelerometer-based method for Simultaneous Extraction of Cardiac and Respiration Gating Signals for Nuclear Medicine Imaging




AuthorsMojtaba Jafari Tadi

PublisherÅbo Akademi and University of Turku

Publishing placeTurku, Finland

Publication year2014


Abstract

Both respiratory and cardiac motions devastate the quality and reliability of medical imaging specifically in nuclear medicine imaging. Motion artifacts can be eliminated by gating the image acquisition based on the respiratory phase and cardiac contractions (dual gating) in PET/CT imaging. Nevertheless, currently there are no clinically approved dual gating approaches in nuclear medicine imaging. The aim of this study was conducted to investigate the feasibility of the accelerometer-based method in dual gating technique. Electrocardiography (ECG), 3-axis accelerometer and respiration belt data were processed and analyzed from ten healthy volunteers. Seismocardiography (SCG) is a non-invasive accelerometer-based method that measures accelerations caused by respiration and myocardial movements in the chest wall using an MEMS accelerometer mounted on the chest of the subjects. The SCG provides accelerometer derived respiratory (ADR) data and the accurate information about quiescent phases within cardiac cycle according to the chest wall movement and mechanical states of the heart, respectively. Furthermore, periods of systole and diastole within a cardiac cycle were measured accurately. The accelerometer-based method can be used to assess the mechanical activity of heart by detecting aortic opening (AO) and aortic closure (AC) events from the SCG signal. The correct information about the status of ventricles and atria helps us to create an improved estimate for quiescent phases within a cardiac cycle. The correlation of ADR signals with the reference respiration belt was investigated using Pearson correlation. High linear correlation was observed between accelerometer-based measurement and reference measurement methods (ECG and respiration belt). Above all, due to the simplicity of the proposed method, the technique has high potential to be applied in dual gating in clinical cardiac Positron Emission Tomography (PET) to obtain motion free images in the future.




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