Reducing overdiagnosis by polygenic risk-stratified screening: findings from the Finnish section of the ERSPC
: Pashayan N, Pharoah PDP, Schleutker J, Talala K, Tammela TLJ, Maattanen L, Harrington P, Tyrer J, Eeles R, Duffy SW, Auvinen A
Publisher: NATURE PUBLISHING GROUP
: 2015
: British Journal of Cancer
: BRITISH JOURNAL OF CANCER
: BRIT J CANCER
: 113
: 7
: 1086
: 1093
: 8
: 0007-0920
DOI: https://doi.org/10.1038/bjc.2015.289
Conclusion: Targeting screening to men at higher polygenic risk could reduce the proportion of cancers overdiagnosed.