Refereed journal article or data article (A1)

Investigation of double bond conversion, mechanical properties, and antibacterial activity of dental resins with different alkyl chain length quaternary ammonium methacrylate monomers (QAM)




List of AuthorsHe JW, Soderling E, Vallittu PK, Lassila LVJ

PublisherTAYLOR & FRANCIS LTD

Publication year2013

JournalJournal of Biomaterials Science, Polymer Edition

Journal name in sourceJOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION

Journal acronymJ BIOMAT SCI-POLYM E

Number in series5

Volume number24

Issue number5

Start page565

End page573

Number of pages9

ISSN0920-5063

DOIhttp://dx.doi.org/10.1080/09205063.2012.699709


Abstract
In order to endow dental resin with antibacterial activity, a series of antibacterial quaternary ammonium methacrylate monomers (QAM) with different substituted alkyl chain length (from 10 to 18) were incorporated into commonly used 2,2-bis[4-(2-hydroxy-3-methacryloyloxy-propoxy)-phenyl]propane (Bis-GMA)/triethyleneglycol dimethacrylate (TEGDMA) (50wt/50wt) dental resin as immobilized antibacterial agents. Double bond conversion (DC), flexural strength (FS) and modulus (FM), and young and mature biofilms inhibition effectiveness of prepared dental resins were studied and Bis-GMA/TEGDMA without QAM was used as reference. Results showed that there was no significant difference on DC, FS, and FM between copolymer with and without 5wt% QAM. Substituted alkyl chain length of QAM had no influence on DC, FS, and FM of copolymer, but had influence on antibacterial activity of copolymer. Antibacterial activity of copolymer increased with increasing of substituted alkyl chain length of QAM, and the sequence followed as 5%C10<5%C11 approximate to 5%C12<5%C16 approximate to 5%C18. Copolymers containing C18 and C16 had the best inhibition effectiveness on both young biofilm and mature biofilm, copolymers containing C12 and C11 only had inhibition effectiveness on young biofilm and copolymer containing C10 had none inhibition effectiveness on neither young biofilm nor mature biofilm.


Research Areas


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