Insulin resistance is associated with poorer verbal fluency performance in women - UTU Research Portal

A1 Refereed original research article in a scientific journal

Insulin resistance is associated with poorer verbal fluency performance in women

Authors: Ekblad LL, Rinne JO, Puukka PJ, Laine HK, Ahtiluoto SE, Sulkava RO, Viitanen MH, Jula AM

Publisher: SPRINGER

Publication year: 2015

Journal: Diabetologia

Journal name in source: DIABETOLOGIA

Journal acronym: DIABETOLOGIA

Volume: 58

Issue: 11

First page : 2545

Last page: 2553

Number of pages: 9

ISSN: 0012-186X

DOI: https://doi.org/10.1007/s00125-015-3715-4

Abstract

Conclusions/interpretation To our knowledge, this is the first comprehensive, population-based study, including both young and middle-aged adults, to report that female sex impacts the association of HOMA-IR with verbal fluency. Our study was cross-sectional, so causal effects of HOMA-IR on cognition could not be evaluated. However, our results suggest that HOMA-IR could be an early marker for an increased risk of cognitive decline in women.