Hippocampal and prefrontal atrophy in patients with early non-demented Parkinson's disease is related to cognitive impairment



: Bruck A, Kurki T, Kaasinen V, Vahlberg T, Rinne JO

Publisher: B M J PUBLISHING GROUP

: 2004

: Journal of Neurology, Neurosurgery and Psychiatry

: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

: J NEUROL NEUROSUR PS

: 75

: 10

: 1467

: 1469

: 3

: 0022-3050

DOI: https://doi.org/10.1136/jnnp.2003.031237


Conclusions: Non-medicated, non-demented patients with early stage PD show hippocampal and prefrontal atrophy. Impaired memory is related to hippocampal atrophy, whereas sustained attention is related to prefrontal atrophy.



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