A1 Refereed original research article in a scientific journal
Reducing Unnecessary Biopsy During Prostate Cancer Screening Using a Four-Kallikrein Panel: An Independent Replication
Authors: Vickers A, Cronin A, Roobol M, Savage C, Peltola M, Pettersson K, Scardino PT, Schroder F, Lilja H
Publisher: AMER SOC CLINICAL ONCOLOGY
Publication year: 2010
Journal: Journal of Clinical Oncology
Journal name in source: JOURNAL OF CLINICAL ONCOLOGY
Journal acronym: J CLIN ONCOL
Number in series: 15
Volume: 28
Issue: 15
First page : 2493
Last page: 2498
Number of pages: 6
ISSN: 0732-183X
DOI: https://doi.org/10.1200/JCO.2009.24.1968
Abstract
We have replicated our previously published finding that a panel of four kallikreins can predict the result of biopsy for prostate cancer in men with elevated PSA. Use of this panel would dramatically reduce biopsy rates. A small number of men with cancer would be advised against immediate biopsy, but these men would have predominately low-stage, low-grade disease.
We have replicated our previously published finding that a panel of four kallikreins can predict the result of biopsy for prostate cancer in men with elevated PSA. Use of this panel would dramatically reduce biopsy rates. A small number of men with cancer would be advised against immediate biopsy, but these men would have predominately low-stage, low-grade disease.