A1 Refereed original research article in a scientific journal

Reducing Unnecessary Biopsy During Prostate Cancer Screening Using a Four-Kallikrein Panel: An Independent Replication




AuthorsVickers A, Cronin A, Roobol M, Savage C, Peltola M, Pettersson K, Scardino PT, Schroder F, Lilja H

PublisherAMER SOC CLINICAL ONCOLOGY

Publication year2010

Journal: Journal of Clinical Oncology

Journal name in sourceJOURNAL OF CLINICAL ONCOLOGY

Journal acronymJ CLIN ONCOL

Number in series15

Volume28

Issue15

First page 2493

Last page2498

Number of pages6

ISSN0732-183X

DOIhttps://doi.org/10.1200/JCO.2009.24.1968


Abstract
We have replicated our previously published finding that a panel of four kallikreins can predict the result of biopsy for prostate cancer in men with elevated PSA. Use of this panel would dramatically reduce biopsy rates. A small number of men with cancer would be advised against immediate biopsy, but these men would have predominately low-stage, low-grade disease.



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