A1 Refereed original research article in a scientific journal

Randomized, placebo-controlled trial of clodronate in patients with primary operable breast cancer



Authors: Powles T, Paterson S, Kanis JA, McCloskey E, Ashley S, Tidy A, Rosenqvist K, Smith I, Ottestad L, Legault S, Pajunen M, Nevantaus A, Mannisto E, Suovuori A, Atula S, Nevalainen J, Pylkkanen L

Publisher: LIPPINCOTT WILLIAMS & WILKINS

Publication year: 2002

Journal:Journal of Clinical Oncology

Journal name in sourceJOURNAL OF CLINICAL ONCOLOGY

Journal acronym: J CLIN ONCOL

Volume: 20

Issue: 15

First page : 3219

Last page: 3224

Number of pages: 6

ISSN: 0732-183X

DOI: https://doi.org/10.1200/JCO.2002.11.080


Abstract
Conclusion: Clodronate, given to patients with primary operable breast cancer, may reduce the occurrence of bone metastases, although this reduction was only significant during this medication period. There was a significant reduction in mortality. (C) 2002 by American Society of Clinical Oncology.



Last updated on 2025-13-10 at 15:11