Characterization of Intrinsically Disordered Prostate Associated Gene (PAGE5) at Single Residue Resolution by NMR Spectroscopy - UTU Research Portal

A1 Refereed original research article in a scientific journal

Characterization of Intrinsically Disordered Prostate Associated Gene (PAGE5) at Single Residue Resolution by NMR Spectroscopy

Authors: Hellman M, Tossavainen H, Rappu P, Heino J, Permi P

Publisher: PUBLIC LIBRARY SCIENCE

Publication year: 2011

Journal: PLoS ONE

Journal name in source: PLOS ONE

Journal acronym: PLOS ONE

Article number: ARTN e26633

Number in series: 11

Volume: 6

Issue: 11

Number of pages: 11

ISSN: 1932-6203

DOI: https://doi.org/10.1371/journal.pone.0026633

Abstract

Conclusion/Significance: The study stands out as the first time structural characterization of the PAGE family protein and introduces how solution state NMR spectroscopy can be effectively utilized for identification of molecular recognition regions (MoRF) in IDPs, known often as transiently populated secondary structures.