A1 Refereed original research article in a scientific journal

How Much Oxycodone Is Needed for Adequate Analgesia After Breast Cancer Surgery: Effect of the OPRM1 118A>G Polymorphism




AuthorsCajanus K, Kaunisto MA, Tallgren M, Jokela R, Kalso E

PublisherCHURCHILL LIVINGSTONE

Publication year2014

JournalJournal of Pain

Journal name in sourceJOURNAL OF PAIN

Journal acronymJ PAIN

Volume15

Issue12

First page 1248

Last page1256

Number of pages9

ISSN1526-5900

DOIhttps://doi.org/10.1016/j.jpain.2014.09.002(external)


Abstract

Perspective: This study demonstrates that the OPRM1 118A>G polymorphism was associated with the amount of oxycodorie required in the immediate postoperative period. Although a significant factor for determining oxycodone requirement, the 118A>G polymorphism alone explained less than 1% of the variance. No association was found between 118A>G and experimental pain. (C) 2014 by the American Pain Society




Last updated on 2024-26-11 at 19:28