A1 Refereed original research article in a scientific journal

Effects of Acute and One-Week Fatty Acid Lowering on Cardiac Function and Insulin Sensitivity in Relation with Myocardial and Muscle Fat and Adiponectin Levels



Authors: Lehto HR, Parkka J, Borra R, Tuunanen H, Lepomaki V, Parkkola R, Knuuti J, Nuutila P, Iozzo P

Publisher: ENDOCRINE SOC

Publication year: 2012

Journal: Journal of Clinical Endocrinology and Metabolism

Journal name in source: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Journal acronym: J CLIN ENDOCR METAB

Number in series: 9

Volume: 97

Issue: 9

First page : 3277

Last page: 3284

Number of pages: 8

ISSN: 0021-972X

DOI: https://doi.org/10.1210/jc.2012-1219


Abstract
Conclusions: A 1-wk FFA depletion suppressed cardiac function and improved insulin sensitivity. Intracellular triglyceride deposits in the heart and skeletal muscle played no role in the observed changes. Our data show that FFA participate in the physiological regulation of adipokine levels. (J Clin Endocrinol Metab 97: 3277-3284, 2012)



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