A1 Refereed original research article in a scientific journal

Paraoxonase-1 and oxidized lipoprotein lipids. The Cardiovascular Risk in Young Finns Study



Authors: Kresanov P, Vasankari T, Ahotupa M, Kaikkonen J, Hutri-Kahonen N, Juonala M, Kahonen M, Lehtimaki T, Viikari J, Raitakari OT

Publisher: Elsevier Ireland LTD

Publication year: 2015

Journal: Atherosclerosis

Journal name in source: ATHEROSCLEROSIS

Journal acronym: Atherosclerosis

Volume: 241

Issue: 2

First page : 502

Last page: 506

Number of pages: 5

ISSN: 0021-9150

DOI: https://doi.org/10.1016/j.atherosclerosis.2015.06.004


Abstract

Conclusion: Higher PON1 activity is associated with decreased oxLDLlipids levels, but not with oxHDLlipids in a population of young Finnish adults. These findings support the suggestion that PON1 activity may have a role in the oxidation of LDL lipids. There is a strong association between PON1 rs662 polymorphism and PON1 activity, but PON1 rs662 polymorphism is not associated with oxidized lipoprotein lipids and oxLDLprot. (C) 2015 Elsevier Ireland Ltd. All rights reserved.




Keywords:
Atherosclerosis, HDL, Oxidized lipids, Paraoxonase-1, Risk factors for atherosclerosis



Last updated on 26/11/2024 05:18:12 PM