A1 Refereed original research article in a scientific journal

Elevated serum angiopoietin-like protein 6 in women with subsequent pregnancy-induced hypertension – a preliminary study




Subtitlea preliminary study

AuthorsTuuri Anna L, Jauhiainen Matti S, Ehnholm Christian P, Tikkanen Matti J, Nicholls M Gary, Kaaja Risto J

Publication year2013

JournalHypertension in Pregnancy

Number in series3

Volume32

Issue3

First page 203

Last page213

Number of pages11

ISSN1064-1955

DOIhttps://doi.org/10.3109/10641955.2013.784783


Abstract

Objective: Association of maternal angiopoietin-like protein 6 (Angptl6) levels with subsequent development of pregnancy-induced hypertension (PIH). Methods: At 24 and 32 weeks of gestation in 47 relatively overweight (BMI ≥ 24 kg/m2), nulliparous pregnant women serum concentrations of Angptl6 were quantified prospectively. Insulin sensitivity and lipids were measured at 24 weeks. Results: Angptl6 levels at 24 weeks, but not at 32 weeks, were significantly higher in women with subsequent PIH. Metabolic factors at 24 weeks did not correlate with Angptl6 levels. Conclusion: This preliminary study suggests that in the second trimester, Angptl6 levels are higher in women with subsequent PIH.


Read More: http://informahealthcare.com/doi/full/10.3109/10641955.2013.784783



Last updated on 2024-26-11 at 15:55