A1 Refereed original research article in a scientific journal
Elevated serum angiopoietin-like protein 6 in women with subsequent pregnancy-induced hypertension – a preliminary study
Subtitle: a preliminary study
Authors: Tuuri Anna L, Jauhiainen Matti S, Ehnholm Christian P, Tikkanen Matti J, Nicholls M Gary, Kaaja Risto J
Publication year: 2013
Journal: Hypertension in Pregnancy
Number in series: 3
Volume: 32
Issue: 3
First page : 203
Last page: 213
Number of pages: 11
ISSN: 1064-1955
DOI: https://doi.org/10.3109/10641955.2013.784783
Abstract
Objective: Association of maternal angiopoietin-like protein 6 (Angptl6) levels with subsequent development of pregnancy-induced hypertension (PIH). Methods: At 24 and 32 weeks of gestation in 47 relatively overweight (BMI ≥ 24 kg/m2), nulliparous pregnant women serum concentrations of Angptl6 were quantified prospectively. Insulin sensitivity and lipids were measured at 24 weeks. Results: Angptl6 levels at 24 weeks, but not at 32 weeks, were significantly higher in women with subsequent PIH. Metabolic factors at 24 weeks did not correlate with Angptl6 levels. Conclusion: This preliminary study suggests that in the second trimester, Angptl6 levels are higher in women with subsequent PIH.
Read More: http://informahealthcare.com/doi/full/10.3109/10641955.2013.784783
Objective: Association of maternal angiopoietin-like protein 6 (Angptl6) levels with subsequent development of pregnancy-induced hypertension (PIH). Methods: At 24 and 32 weeks of gestation in 47 relatively overweight (BMI ≥ 24 kg/m2), nulliparous pregnant women serum concentrations of Angptl6 were quantified prospectively. Insulin sensitivity and lipids were measured at 24 weeks. Results: Angptl6 levels at 24 weeks, but not at 32 weeks, were significantly higher in women with subsequent PIH. Metabolic factors at 24 weeks did not correlate with Angptl6 levels. Conclusion: This preliminary study suggests that in the second trimester, Angptl6 levels are higher in women with subsequent PIH.
Read More: http://informahealthcare.com/doi/full/10.3109/10641955.2013.784783
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