Ruut Laitio - UTU Research Portal

Ruut Laitio

- Docent,
Anaesthesiology, Intensive Care (Department of Clinical Medicine)

ruut.laitio@utu.fi

Publications

1 of 3

Effects of intranasal dexmedetomidine premedication on hemodynamics, oxygenation and bleeding in patients undergoing total knee arthroplasty under spinal anesthesia - a secondary analysis of a prospective, double-blinded, randomized controlled trial (TKADEX)A metabolic profile of xenon and metabolite associations with 6-month mortality after out-of-hospital cardiac arrest : A post-hoc study of the randomised Xe-Hypotheca trial (2025)
- Journal of Clinical AnesthesiaPLoS ONE
Tiainen, Suvi-Maria; Koskinen, Atte; Mäkelä, Sanna; Laitio, Ruut; Löyttyniemi, Eliisa; Mäkelä, Keijo; Pirttikangas, Carl-Olof; Saari, Teijo I.; Uusalo, Panu
(A1 Refereed original research article in a scientific journal)
Evaluation of myocardial work indices during targeted temperature management in cardiac arrest patientsAkuutisti sairaan potilaan nestehoidon periaatteet (2025)
- European heart journal open
Ballo, Haitham; Saraste, Antti; Laitio, Ruut; Arola, Olli ; Airaksinen, Juhani; Pietilä, Mikko; Harjola, Veli-Pekka; Varpula, Marjut; Vahlberg, Tero; Laitio, Timo
(Abstract)
Grey matter volume reduction and its association with brain-enriched blood biomarkers in out-of-hospital cardiac arrest survivors (2025)
- Scientific ReportsNeuroradiology
Hollmén, Carita C.; Vorobyev, Victor; Parkkola, Riitta; Posti, Jussi P.; Saunavaara, Jani; Laitio, Ruut; Arola, Olli; Hynninen, Marja; Bäcklund, Minna; Blennow, Kaj; Zetterberg, Henrik; Martola, Juha; Ylikoski, Emmi; Roine, Risto O.; Tiainen, Marjaana; Scheinin, Harry; Maze, Mervyn; Vahlberg, Tero; Laitio, Timo T.; Xe-HYPOTHECA Consortium
(A1 Refereed original research article in a scientific journal)
Neuroprotective Effects of Inhaled Xenon Gas on Brain Structural Gray Matter Changes After Out-of-Hospital Cardiac Arrest Evaluated by Morphometric Analysis: A Substudy of the Randomized Xe-Hypotheca Trial (2025)
- Neurocritical Care
Hollmén, Carita; Parkkola, Riitta; Vorobyev, Viktor; Saunavaara, Jani; Laitio, Ruut; Arola, Olli; Hynninen, Marja; Bäcklund, Minna; Martola, Juha; Ylikoski, Emmi; Roine, Risto O.; Tiainen, Marjaana; Scheinin, Harry; Maze, Mervyn; Vahlberg, Tero; Laitio, Timo T.
(A1 Refereed original research article in a scientific journal)
Premedication with intranasal dexmedetomidine in patients undergoing total knee arthroplasty under spinal anaesthesia (TKADEX)—a prospective, double-blinded, randomised controlled trial (2025)
- BJA Open
Tiainen, Suvi-Maria; Heinonen, Heta; Koskinen, Atte; Mäkelä, Sanna; Laitio, Ruut; Löyttyniemi, Eliisa; Mäkelä, Keijo; Saari, Teijo I.; Uusalo, Panu
(A1 Refereed original research article in a scientific journal)
Akuutisti sairaan potilaan nestehoidon periaatteet (2024) Tehohoito-opas Laitio, Ruut; Reinikainen, Matti
(D2 Article in a professional compilation book)
(2024)
Nummela, Aleksi J.; Scheinin, Harry; Perola, Markus; Joensuu, Anni; Laitio, Ruut; Arola, Olli; Grönlund, Juha; Roine, Risto O.; Bäcklund, Minna; Vahlberg, Tero J.; Laitio, Timo; Xe-Hypotheca Collaboration Group
(A1 Refereed original research article in a scientific journal)
One-year healthcare costs of patients with spontaneous intracerebral hemorrhage treated in the intensive care unit (2023) Akuuttihoito-opas Laitio Ruut, Reinikainen Matti
(D2 Article in a professional compilation book)
Comparison of the prognostic value of early-phase proton magnetic resonance spectroscopy and diffusion tensor imaging with serum neuron-specific enolase at 72 h in comatose survivors of out-of-hospital cardiac arrest-a substudy of the XeHypotheca trialTrends in Mortality after Intensive Care of Patients with Aneurysmal Subarachnoid Hemorrhage in Finland in 2003-2019: A Finnish Intensive Care Consortium study (2023)
Koskensalo Kalle, Virtanen Sami, Saunavaara Jani, Parkkola Riitta, Laitio Ruut, Arola Olli, Hynninen Marja, Silvasti Päivi, Nukarinen Eija, Martola Juha, Silvennoinen Heli M, Tiainen Marjaana, Roine Risto O, Scheinin Harry, Saraste Antti, Maze Mervyn, Vahlberg Tero, Laitio Timo T; XeHYPOTHECA Research Group
(A1 Refereed original research article in a scientific journal)
Effect of antiplatelet and anticoagulant medication use on injury severity and mortality in patients with traumatic brain injury treated in the intensive care unit (2023)
- Acta Neurochirurgica
Vehviläinen J, Virta JJ, Skrifvars MB, Reinikainen M, Bendel S, Ala-Kokko T, Hoppu S, Laitio R, Siironen J, Raj R
(A1 Refereed original research article in a scientific journal)
Effect of xenon on brain injury, neurological outcome, and survival in patients after aneurysmal subarachnoid hemorrhage-study protocol for a randomized clinical trial (2023)
- Trials
Laaksonen Mikael, Rinne Jaakko, Rahi Melissa, Posti Jussi P., Laitio Ruut, Kivelev Juri, Saarenpää Ilkka, Laukka Dan, Frösen Juhana, Ronkainen Antti, Bendel Stepani, Långsjö Jaakko, Ala-Peijari Marika, Saunavaara Jani, Parkkola Riitta, Nyman Mikko, Martikainen Ilkka K., Dickens Alex M., Rinne Juha, Valtonen Mika, Saari Teijo I., Koivisto Timo, Bendel Paula, Roine Timo, Saraste Antti, Vahlberg Tero, Tanttari Juha, Laitio Timo
(A1 Refereed original research article in a scientific journal)
Incidence and risk factors of posttraumatic hydrocephalus and its association with outcome following intensive care unit treatment for traumatic brain injury: a multicenter observational study (2023)
- Journal of Neurosurgery
Lindfors Matias, Vehviläinen Juho, Bendel Stepani, Reinikainen Matti, Laitio Ruut, Ala-Kokko Tero, Hoppu Sanna, Siironen Jari, Skrifvars Markus B, Raj Rahul
(A1 Refereed original research article in a scientific journal)
Early thrombocytopenia is associated with an increased risk of mortality in patients with traumatic brain injury treated in the intensive care unit: a Finnish Intensive Care Consortium study (2022)
- Acta Neurochirurgica
Lillemäe Kadri, Luostarinen Teemu, Reinikainen Matti, Bendel Stepani, Laitio Ruut, Hoppu Sanna, Ala-Kokko Tero, Niemi Tomi, Skrifvars Markus B, Raj Rahul
(A1 Refereed original research article in a scientific journal)
External validation of the NeuroImaging Radiological Interpretation System and Helsinki computed tomography score for mortality prediction in patients with traumatic brain injury treated in the intensive care unit: a Finnish intensive care consortium study (2022)
- Acta Neurochirurgica
Vehviläinen Juho, Skrifvars Markus, Reinikainen Matti, Bendel Stepani, Laitio Ruut, Hoppu Sanna, Ala-Kokko Tero, Siironen Jari, Raj Rahul
(A1 Refereed original research article in a scientific journal)
(2022)
- European Stroke Journal
Smeds Marika, Skrifvars Markus B, Reinikainen Matti, Bendel Stepani, Hoppu Sanna, Laitio Ruut, Ala-Kokko Tero, Curtze Sami, Sibolt Gerli, Martinez-Majander Nicolas, Raj Rahul
(A1 Refereed original research article in a scientific journal)
(2022)
- Neurocritical Care
Virta Jyri J., Skrifvars Markus, Reinikainen Matti, Bendel Stepani, Laitio Ruut, Hoppu Sanna, Ala-Kokko Tero, Siironen Jari, Raj Rahul
(A1 Refereed original research article in a scientific journal)
Trends in mortality after intensive care of patients with traumatic brain injury in Finland from 2003 to 2019: a Finnish Intensive Care Consortium study (2022)
- Acta Neurochirurgica
Luostarinen Teemu, Vehviläinen Juho, Lindfors Matias, Reinikainen Matti, Bendel Stepani, Laitio Ruut, Hoppu Sanna, Ala-Kokko Tero, Skrifvars Markus, Raj Rahul
(A1 Refereed original research article in a scientific journal)
Effect of Inhaled Xenon on Cardiac Function in Comatose Survivors of Out-of-Hospital Cardiac Arrest—A Substudy of the Xenon in Combination With Hypothermia After Cardiac Arrest Trial (2021)
- Critical Care Explorations
Saraste Antti, Ballo Haitham, Arola Olli, Laitio Ruut, Airaksinen Juhani, Hynninen Marja, Bäcklund Minna, Ylikoski Emmi, Wennervirta Johanna, Pietil Mikko, Roine Risto O., Harjola Veli-Pekka, Niiranen Jussi, Korpi Kirsi, Varpula Marjut, Scheinin Harry, Maze Mervyn, Vahlberg Tero, Laitio Timo
(A1 Refereed original research article in a scientific journal)
One-year costs of intensive care in pediatric patients with traumatic brain injury (2021)
- Journal of Neurosurgery: Pediatrics
Mikkonen Era D, Skrifvars Markus B, Reinikainen Matti, Bendel Stepani, Laitio Ruut, Hoppu Sanna, Ala-Kokko Tero, Karppinen Atte, Raj Rahul
(A1 Refereed original research article in a scientific journal)
Psychotropic medication use among patients with a traumatic brain injury treated in the intensive care unit: a multi-centre observational study (2021)
- Acta Neurochirurgica
Vehviläinen Juho, Skrifvars Markus B, Reinikainen Matti, Bendel Stepani, Marinkovic Ivan, Ala-Kokko Tero, Hoppu Sanna, Laitio Ruut, Siironen Jari, Raj Rahul
(A1 Refereed original research article in a scientific journal)