Kari Auranen
Ph.D. (biometry, Helsinki University, 1999)
Department of Mathematics and Statistics kajuaur@utu.fi +358 29 450 4320 +358 50 350 6920 Vesilinnantie 5 Turku |
statistical analysis of cohort studies; evaluation of the effects of vaccination and infection mitigation; mathematical models of infection transmission
statistical analysis of infectious disease data; evaluation of population-level effects of vaccination; endpoints in vaccine trials.
I am currently a Professor of Statistics at the Department of Mathematics and Statistics and the Department of Clinical Medicine of the University of Turku (Finland). Before moving to Turku, I worked for almost 20 years on vaccination-related research questions at the Finnish Institute for Health and Welfare.
My own research interests include statistical modelling and analysis of infectious disease data, estimation of vaccine efficacy from trial and field data, dynamics of pneumococcal carriage and its relation to disease, and the effects of vaccination on the epidemiology of the pneumococcus. I have a special interest in Bayesian analysis of incompletely observed infectious disease data and Markov chain Monte Carlo methods applied to deal with the problem. My recent publications in the field of infectious disease data include a survey study of the intensity of social contacts and an analysis of the effectiveness of case isolation and quarantine during the early phase of the SARS-CoV-2 pandemic in Finland. Through my students, I have recently become involved in the analysis of causal mediation in cohort and microbiome studies.
My teaching revolves around various topics related to biostatistics, with emphasis on real-life data analysis and statistical modelling. My recent lecture courses include "Survival analysis", "Design of experiments" and "Statistical methods in epidemiology".
- Mitigation of biases in estimating hazard ratios under non-sensitive and non-specific observation of outcomes-applications to influenza vaccine effectiveness (2021)
- Emerging Themes in Epidemiology
(A1 Refereed original research article in a scientific journal) - Social Distancing and SARS-CoV-2 Transmission Potential Early in the Epidemic in Finland (2021)
- Epidemiology
(A1 Refereed original research article in a scientific journal) - Spotlight influenza: Estimation of influenza vaccine effectiveness in elderly people with assessment of residual confounding by negative control outcomes, Finland, 2012/13 to 2019/20 (2021)
- Eurosurveillance
(A1 Refereed original research article in a scientific journal) - Changing epidemiology of methicillin-resistant Staphylococcus aureus in a low endemicity area- new challenges for MRSA control (2020)
- European Journal of Clinical Microbiology and Infectious Diseases
(A1 Refereed original research article in a scientific journal) - Cohort study design for estimating the effectiveness of seasonal influenza vaccines in real time based on register data: The Finnish example (2020)
- Scandinavian Journal of Public Health
(A1 Refereed original research article in a scientific journal) - COVID-19-tutkimuskatsaus 8/2020 (2020) Vapalahti, Olli; Sironen, Tarja; Pimenoff, Ville; Auranen, Kari; Leino, Tuija; Karvonen, Sakari; Toivanen, Otto; Ylöstalo, Hanna; Vainikainen, Mari-Pauliina; Mäkinen, Saku; Arponen, Anni; Heinikoski, Saila; Limnéll, Jarno; Salo, Ahti
(D4 Published development or research report or study ) - Effectiveness of 10-valent pneumococcal conjugate vaccine estimated with three parallel study designs among vaccine-eligible children in FinlandChanging molecular epidemiology of methicillin-resistant Staphylococcus aureus in Southwest Finland, 2007 - 2016 (2020)
- Vaccine
(A1 Refereed original research article in a scientific journal) - Effectiveness of 2 Influenza Vaccines in Nationwide Cohorts of Finnish 2-Year-Old Children in the Seasons 2015-2016 Through 2017-2018 (2020)
- Clinical Infectious Diseases
(A1 Refereed original research article in a scientific journal) - Impact and effectiveness of a conjugate vaccine against invasive pneumococcal disease in Finland-a modelling approachLong-term impact of 10-valent pneumococcal conjugate vaccination on invasive pneumococcal disease among children in Finland (2020)
- Human Vaccines and ImmunotherapeuticsVaccine
(A1 Refereed original research article in a scientific journal) - Koronaepidemian mallinnuksen lähtökohdat, tavoitteet ja ongelmat (2020)
- Duodecim
(A2 Refereed review article in a scientific journal ) - Capturing multiple-type interactions into practical predictors of type replacement following human papillomavirus vaccination (2019)
- Philosophical Transactions B: Biological SciencesJournal of Clinical Microbiology
(A1 Refereed original research article in a scientific journal) - Effectiveness of the ten-valent pneumococcal Haemophilus influenzae protein D conjugate vaccine (PHiD-CV10) against all respiratory tract infections in children under two years of ageAcquisition and Transmission of Streptococcus pneumoniae Are Facilitated during Rhinovirus Infection in Families with Children (2019)
- Vaccine
(A1 Refereed original research article in a scientific journal) - Fast approximate computation of cervical cancer screening outcomes by a deterministic multiple-type HPV progression model (2019)
- Mathematical Biosciences
(A1 Refereed original research article in a scientific journal) - (2018) Jenna Junnila, Tiina Hirvioja, Kaisu Rantakokko-Jalava, Kari Auranen, Esa Rintala, Laura Lindholm, Jaakko Silvola, Harri Marttila, Anu Harttio-Nohteri, Kirsi Gröndahl-Yli-Hannuksela, Jaana Vuopio
(Other publication) - F-18-FDG-PET/CT based total metabolic tumor volume change during neoadjuvant chemotherapy predicts outcome in advanced epithelial ovarian cancerObesity, Underweight, and Smoking are Associated with Worse Cardiorespiratory Fitness in Finnish Healthy Young Men: a Population-Based Study (2018)
- European Journal of Nuclear Medicine and Molecular Imaging
(A1 Refereed original research article in a scientific journal) - (2018)
(A1 Refereed original research article in a scientific journal) - Surveillance of Circulating Bordetella pertussis Strains in Europe during 1998 to 2015 (2018)
(A1 Refereed original research article in a scientific journal) - (2017)
- American Journal of Respiratory and Critical Care Medicine
(A1 Refereed original research article in a scientific journal) - Epidemiology of hepatitis B infection in Finland: Implications for immunisation policy (2017)
- Vaccine
(A1 Refereed original research article in a scientific journal) - (2017)
- Frontiers in Public Health
(A1 Refereed original research article in a scientific journal)



