Mikko Nikinmaa
Ph.D., Professor of Zoology; FT, Eläintieteen professori
miknik@utu.fi +358 29 450 4222 +358 50 435 1637 Vesilinnantie 5 Turku |
animal physiology; fish biology; aquatic toxicology; environmental biology; respiration; membrane transport; gas transport
Mikko Nikinmaa got his high school diploma (International Baccalaureate)
from the United World College of the Atlantic, Llantwit Major, U.K. His
university education including the Ph. D. degree he accomplished at
University of Helsinki, Finland. He did postdoctoral work in Odense
University, Denmark, and Stanford University, USA. Thereafter he worked
in the University of Helsinki with research visits to University of
British Columbia, Vancouver, and Dalhousie University, Halifax, Nova
Scotia. In 1995 he was appointed Professor of Zoology in the University
of Turku. He was the President of Scandinavian Physiological Society in
1994-1996, and a member of National Research Council of Environment and
Natural Resources in 1995-1997. He served as a Dean of the Faculty of
Mathematics and Natural Sciences in 2000-2004, and was the director of
the Center of Excellence in Evolutionary Genetics and Physiology
(appointed by the Academy of Finland) in 2006-2011. He has been chief
editor of Aquatic Toxicology since 2004 and subject (respiratory and
comparative physiology) editor of Acta Physiologica since 1997.
Presently he is editorial board member in four journals. His more than 200 publications include the books "Vertebrate Red Blood
Cells" (1990, Springer) and "Introduction to Aquatic Toxicology" (2014, Elsevier), and a review on Membrane Transport and the
Control of Haemoglobin Oxygen Affinity in Physiological Reviews. He has
reviewed grant applications to agencies from more than ten different
countries, and served as an evaluator of academic positions in USA,
Canada, U.K., Sweden, South Africa and Finland. More than 30 journals
have used him as peer reviewer. His research interests lie in how
environmental changes, particularly temperature, oxygen and toxicants,
affect cellular functions especially in fish. An important aspect of
research is environmental regulation of gene expression, for example how
toxicants, oxygen and temperature changes affect transcription,
translation and protein stability.
Comparative Physiology, Ecophysiology, Ecotoxicology, Effects of Climate Change on Organism Function, Environmental Regulation of Gene Expression
Responsible Professor of Animal Physiology teaching; Ecophysiology and ecotoxicology as teaching areas
- Oxidative stress during stressful heat exposure and recovery in the North Sea eelpout Zoarces viviparus L. (2006)
- Journal of Experimental Biology
- Oxygen availability regulates metabolism and gene expression in trout hepatocyte cultures (2006)
- AJP - Regulatory, Integrative and Comparative Physiology
- Oxygen-dependent diseases in the retina: Role of hypoxia-inducible factors (2006)
- Experimental Eye Research
- Temperature regulates hypoxia-inducible factor-1 (HIF-1) in a poikilothermic vertebrate, crucian carp (Carassius carassius) (2006)
- Journal of Experimental Biology
- Two different oxygen sensors regulate oxygen-sensitive K+ transport in crucian carp red blood cells (2006)
- Journal of Physiology
- Comments on Point: Counterpoint "Positive effects of intermittent hypoxia (live high: train low) on exercise performance are/are not mediated primarily by augmented red cell volume" (2005) Nikinmaa M
- Hypoxic responses of Na+/K+ ATPase in trout hepatocytes (2005)
- Journal of Experimental Biology
- Oxygen-dependent gene expression in fishes (2005)
- AJP - Regulatory, Integrative and Comparative Physiology
- Pollution related effects on immune function and stress in a free-living population of pied flycatcher Ficedula hypoleuca (2005)
- Journal of Avian Biology
- Baltic salmon (Salmo salar) yolk-sac fry mortality is associated with disturbances in the function of hypoxia-inducible transcription factor (HIF-1 alpha) and consecutive gene expression (2004)
- Aquatic Toxicology
- Effects of short-term copper exposure on gill structure, metallothionein and hypoxia-inducible factor-1 alpha (HIF-1 alpha) levels in rainbow trout (Oncorhynchus mykiss) (2004)
- Aquatic Toxicology
- Physiological stress response to warm and cold acclimation in polar and temperate fish (2004)
- Free Radical Biology and Medicine
- Redox state regulates HIF-1 alpha and its DNA binding and phosphorylation in salmonid cells (2004)
- Journal of Cell Science
- The Bohr effect - a discovery 100 years ago, with intensive studies about the effect of protons on haemoglobin function still going on (2004)
- Acta Physiologica Scandinavica
- beta(3)-Adrenergic receptors - studies on rainbow trout reveal ancient evolutionary origins and functions distinct from the thermogenic response (2003)
- AJP - Regulatory, Integrative and Comparative Physiology
- Dehydroabietic acid, a major component of wood industry effluents, interferes with cellular energetics in rainbow trout hepatocytes (2003)
- Aquatic Toxicology
- Forest management is associated with physiological stress in an old-growth forest passerine (2003)
- Proceedings of the Royal Society B: Biological Sciences
- Heat- and cold-inducible regulation of HSP70 expression in zebrafish ZF4 cells (2003)
- Comparative Biochemistry and Physiology - Part B: Biochemistry and Molecular Biology
- Intracellular pH regulation in rainbow trout (Oncorhynchus mykiss) hepatocytes: the activity of sodium/proton exchange is oxygen-dependent (2003)
- Journal of Comparative Physiology B
- Molecular mechanisms of oxygen-induced regulation of Na+/K+ pump (2003)
- Advances in Experimental Medicine and Biology