Reijo Lahti
reila@utu.fi +358 40 526 5670 Tykistökatu 6 Turku |
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- Toward a quantum-mechanical description of metal-assisted phosphoryl transfer in pyrophosphatase (2001) Heikinheimo P, Tuominen V, Ahonen AK, Teplyakov A, Cooperman BS, Baykov AA, Lahti R, Goldman A
- Engineering a new magnesium binding site in the subunit contact region of Escherichia coli inorganic pyrophosphatase (2000)
- Биохимия / Biochemistry
- Directed mutagenesis studies of the metal binding site at the subunit interface of Escherichia coli inorganic pyrophosphatase (1999)
- Journal of Biological Chemistry
- Evolutionary aspects of inorganic pyrophosphatase (1999)
- FEBS Letters
- Reciprocal effects of substitutions at the subunit interfaces in hexameric pyrophosphatase of Escherichia coli - Dimeric and monomeric forms of the enzyme (1999)
- Journal of Biological Chemistry
- Cloning and expression of a unique inorganic pyrophosphatase from Bacillus subtilis: evidence for a new family of enzymes (1998)
- FEBS Letters
- The R78K and D117E active-site variants of Saccharomyces cerevisiae soluble inorganic pyrophosphatase: Structural studies and mechanistic implications (1998) Tuominen V, Heikinheimo P, Kajander T, Torkkel T, Hyytia T, Kapyla J, Lahti R, Cooperman BS, Goldman A
- Structural and functional consequences of substitutions at the tyrosine 55 lysine 104 hydrogen bond in Escherichia coli inorganic pyrophosphatase (1997) Fabrichniy IP, Kasho VN, Hyytia T, Salminen T, Halonen P, Dudarenkov VY, Heikinheimo P, Chernyak VY, Goldman A, Lahti R, Cooperman BS, Baykov AA
- The three metal ion mechanism of inorganic pyrophosphatases (1997)
- Protein Engineering
- A site-directed mutagenesis study of Saccharomyces cerevisiae pyrophosphatase - Functional conservation of the active site of soluble inorganic pyrophosphatases (1996)
- European Journal of Biochemistry
- The structural basis for pyrophosphatase catalysis (1996)
- Structure
- New crystal forms of Escherichia coli and Saccharomyces cerevisiae soluble inorganic pyrophosphatases (1995)
- Acta Crystallographica Section D: Biological Crystallography
- Structure and function analysis of Escherichia coli inorganic pyrophosphatase: is a hydroxide ion the key to catalysis? (1995)
- Biochemistry
- Characterization of the 5′ flanking region of the Escherichia coli ppa gene encoding inorganic pyrophosphatase: mutations in the ribosome-binding site decrease the level of ppa mRNA (1991)
- Journal of general microbiology
- Genetic engineering of Escherichia coli inorganic pyrophosphatase
Tyr55 and Tyr141 are important for the structural integrity (1991)- European Journal of Biochemistry
- A site-directed mutagenesis study on Escherichia coli inorganic pyrophosphatase. Glutamic acid-98 and lysine-104 are important for structural integrity, whereas aspartic acids-97 and -102 are essential for catalytic activity (1990) LAHTI R, POHJANOKSA K, PITKARANTA T, HEIKINHEIMO P, SALMINEN T, MEYER P, HEINONEN J
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